C-Reactive Protein (CRP) | Vibepedia

C-reactive protein (CRP) is a key acute-phase protein produced by the liver, its levels soaring in response to inflammation. Historically, it was identified in 1930 by Tillet and Francis during studies of *Streptococcus pneumoniae* infections, hence its name. Today, CRP tests are a cornerstone in clinical practice, not just for detecting infection or inflammation but also for assessing cardiovascular risk. While widely accepted as a marker, debates persist regarding the precise interpretation of low-level elevations and the clinical utility of high-sensitivity CRP (hs-CRP) in diverse patient populations. Its rapid rise and fall make it a dynamic indicator of ongoing biological processes.